Antagonism of Glutathione to Antioxidative Capacity Decrease Induced by Manganese Exposure in Rats / 环境与健康杂志
Journal of Environment and Health
; (12)1993.
Article
in Zh
| WPRIM
| ID: wpr-546070
Responsible library:
WPRO
ABSTRACT
Objective To study the antagonism of glutathione(GSH) to antioxidative capacity decrease induced by manganese exposure in rats.Methods 48 healthy male SD rats were randomly divided into six groups: the blank control,GSH control,MnCl2.4H2O(15 mg/kgand 30 mg/kg),15 mg/kgMnCl2.4H2O+1 mmol/kgGSH and 30 mg/kg MnCl2.4H2O+1 mmol/kg GSH,the treatment was conducted through peritoneal injection.The activity of superoxide dismutase(SOD),catalase(CAT) and glutathione peroxidase(GSH-Px)in the serumand the testis were determined bycolorimetric analysis.Results Compared with the blank control group,the activity of SOD,CAT and GSH-Px in the serum and testis in 30 mg/kg groups significantly decreased(P
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Index:
WPRIM
Language:
Zh
Journal:
Journal of Environment and Health
Year:
1993
Type:
Article