The Effects of circadian Rhythm on Tolerance to Acute Hypcxia in Mice / 第三军医大学学报

ABSTRACT

The relationship between circadian rhythm and tolerance to acute hypoxia at a Simula ted altitude of 10000m was studied in 110 micc.Bolh number of survival and surviving time were increased from 3: 00 and reached the hightidc at 5:00.From then the number of survival remained at the same level,the surviving time declined gradually.Both the number of survival and surviving time attained the lowest value at 14: 56 to 0:30.The results suggest: 1.there is a close relationship b etween circadian rhythm and tolerance to acutehypoxia; 2.when rodents arc used for this kind of study,the affect of circadian rhythm should be considered.