Effect of ligustrazine on the calcium contants and calmodulin activity of lung tissue in rats of the bleomycin-induced pulmonary fibrosis / 中国临床药理学与治疗学
Article
in Zh
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| ID: wpr-552760
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WPRO
ABSTRACT
AIM: To observe the effect of ligustrazine on the calcium contents and calmodulin activity of lung tissue in rats of the bleomycin-induced pulmonary fibrosis. METHODS: Thirty-two SD rats were replicated into pulmonary fibrosis models by intratracheal injection of bleomycin A 5 in one lump and were divided into two groups randomly, untreated model group (n=16) and ligustrazine group(n=16). The calcium contents and calmodulin activity of the lung of the rats of each group were assayed on d 14, d 28 after the injection and compared with control group (n=8). RESULTS: The calcium contents and calmodulin activity of model group were obviously higher than control group (P
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Clinical Pharmacology and Therapeutics
Year:
2000
Type:
Article