Establishing an experimental animal model of phallic reconstruction with sensory restoration / 第二军医大学学报
Article
in Zh
| WPRIM
| ID: wpr-555974
Responsible library:
WPRO
ABSTRACT
Objective:
To establish an experimental phalloplasty model with sensory restoration in rabbits and to explore a new surgical technique to improve the postoperative sensory function in phallic reconstruction.Methods:
Adult male New Zealand white rabbit was used. Penile reconstruction was performed with superficial epigastric faciovascular pedicle flap. Free saphenous nerve graft was dissected, embedded in the flap, and end-to-end anastomosed to dorsal nerve of penis. Postoperatively, H-E staining and CGRP immunohistochemical staining were applied to observe the morphology of the regenerated nerves in the reconstructed penis at different stages.Results:
Only a few CGRP-positive fibers scattered in deep corium in the reconstructed penis 1 month after surgery, while the quantity of CGRP nerve fibers increased markedly and the CGRP-positive fibers appeared in both superficial corium and papillae corii after 3 months. Six months postoperatively, the positive nerve fibers were also observed around the cutaneous accessories and in the epidermis-corium boundary layer.Conclusion:
This rabbit model demonstrates the possibility of a new method for phalloplasty with sensory recovery, which may redound to clinical application.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Academic Journal of Second Military Medical University
Year:
1982
Type:
Article