Study on the expression of ?-SMA in rats with adriamycin-induced nephrothy and intervention of Valsartan on it / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1986.
Article
in Zh
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| ID: wpr-556764
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WPRO
ABSTRACT
Aim To observe the changes on the expression of ?-SMA in rats with adriamycin-induced nephrothy and intervention of Valsartan. Methods The model group were made by unilateral nephrectomy with twice-adriamycin injections by caudal vein. Immunohistochemical method, flow cytometry and pathologic image analysis were used to observe the expression of ?-SMA, FN and LN in rats. Results The expression of ?-SMA was positive in the model group. Rates of positive cell and protein semi-quantitative analysis were more higher than the sham group(P
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
1986
Type:
Article