Progress in new drugs targeting reverse cholesterol transport / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)2003.
Article
in Zh
| WPRIM
| ID: wpr-559732
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WPRO
ABSTRACT
Numerous epidemiologic studies have shown that there is a strong inverse relationship between high-density lipoprotein cholesterol levels and artherosclerosis. The first atheroprotective mechanism of HDL is the RCT(reverse cholesterol transport). Recently,considerable pharmacological trials have focused on targeting critical proteins and enzymes in RCT including apoAⅠ, ATP binding cassette transporter A1 and cholesteryl ester transport protein etc. A number of new drugs have demonstrated conspicuous protective effects on artherosclerosis. Therefore RCT will become an attractive target for prevention and cure of dyslipidamia and artherosclerosis.
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WPRIM
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
2003
Type:
Article