Correlation between MDR1 genetic polymorphism and prognosis in acute leukemia / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1986.
Article
in Zh
| WPRIM
| ID: wpr-561699
Responsible library:
WPRO
ABSTRACT
Multidrug resistance is a common form of drug resistance of tumors and one main reason for chemotherapy′s failure and recrudescence of acute leukemia. In recent years,substantial studies addressed the different aspects about MDR1,including MDR1 genetic polymorphism,mRNA/protein expression as well as the function of its coding protein (P-gp).This paper reviewed recent advances about the relation between MDR1 genetic polymorphism and acute leukemia prognosis with the aim to improve acute leukemia curing and chemotherapy outcome evaluating in China.
Full text:
1
Index:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
1986
Type:
Article