Progress in the study on animal model of diabetic nephropathy / 中国药理学通报

ABSTRACT

Diabetic nephropathy(DN) greatly affects human health.It is critical to select suitable animal model for the research on the disease.In the paper,the status quo of domestic and abroad research related to animal model is analyzed,pointing out the advantage and disadvantage of drug-induced,spontaneous and transgenic animal model.Comparision is made between different etiopathogenesis,symptoms and renal pathological changes in each mode.It is to consummate DN related models and provide laboratory flat for pharmaceutic research on DN.