ULTRASTRUCTURES OF THE HEPATOMA CELL LINES FSK 7901, FSK 7902 OF RAT / 解剖学报

ABSTRACT

This paper presents the results of an ultrustructural study of the hepatoma cell lines FSK 7901, FSK 7902 of long term cultures about 2 years more.The size of cell varies. Distribution of the cell is single or in epitheloid monolayer. Pseudopodial processes or microvilli cover the perimeter of certain hepatoma cells. In the monolayer, the microvilli exist where the neighboring plasmalemmae are in loose contact. When their contact is close, the neighboring plasmalemmae may be straight, wavelike or interdigitated. The nucleus and enlarged nucleoli are irregu- lar in shape. The deformity of nucleolonema is remarkable.Rough endoplasmic reticulum (RER) and mitochondria are much less in number in the cytoplasm, but the free ribosomes is very abundant. The shape of mitochondria and their cristae are irregular. The Golgi complex is often or less arranged around 10 in a group, situated near the nucleus. Typical coucentric body from RER or SER has not been observed. Annulate lamellae are easily found. A peculiar structure, primordial rough-surfaced endoplasmic reticulum (PRER) is seen.Juxta-nuclear acidophilic area consists of a group of Goigi complex or Golgi complex and mitochondria.