Comparison of Effects of Xiaoyu Tablets and its Constituents on Endothelin-1 and Nitric Oxide in Atherosclerotic Rabbits / 中成药
Chinese Traditional Patent Medicine
; (12)1992.
Article
in Zh
| WPRIM
| ID: wpr-570029
Responsible library:
WPRO
ABSTRACT
Objective:
To determine the rationality of prescription of Xiaoyu tablets.Methods:
The effects of Xiaoyu tablets and its single constituents on endothelin-1(ET-1) and nitric oxide(NO) in atherosclerotic rabbits were observed.Results:
Xiaoyu tablets showed stronger actions than its single constituents (extract of radix salviae miltiorrhizae or fructus crataegi) in decreasing the contents of ET-1 in plasma and atherosclerotic vessel wall and increasing the contents of NO in serum and atherosclerotic vessel wall.Conclusion:
There was the obvious synergism on reduction of ET-1 and elevation of NO in atheroscleerotic rabbits when both extracts of the Chinese herbal medicines were simultaneously used.
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Traditional Patent Medicine
Year:
1992
Type:
Article