The relationship between amino-acid motif of HLA-DR?1*04(?chain) and the susceptibility to rheumatoid arthritis / 中华风湿病学杂志
Chinese Journal of Rheumatology
; (12)2001.
Article
in Zh
| WPRIM
| ID: wpr-572133
Responsible library:
WPRO
ABSTRACT
Objective To investigate the susceptibility to rheumatoid arthritis (RA) with HLA- DR?1*04 subtypes.Methods One hundred and thirty-six RA patients and 79 patients with other rheumatic diseases were recruited in this study.HLA typing was performed using high-resolution PCR-SSP DNA techniques.The clinical features and serologic markers between different motifs were analyzed.Results Compared with other rheumatic diseases,the frequency of HLA-DR?1*04 alleles in RA patients was significantly increased(33.8% vs 12.7%)(OR=3.52,95%CI=1.43~5.43,P
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Rheumatology
Year:
2001
Type:
Article