Anticoagulation Effects of Supplemented Salvia Beverage on Experimental Myocardial Ischemia in Rats / 中国中医药信息杂志

ABSTRACT

Objective To study the anticoagulation effects of Supplemented Salvia Beverage (SSB) on myocardial ischemia in rats. Methods Rat myocardial ischemia model was induced by occluding the left anterior descending coronary artery,the effects of SSB (8.24,4.12,2.06 g/kg) on the activated partial thromboplastin time (APTT),prothrombin time (PT),thrombin Time (TT),platelet adherence rate,platelet aggregation,length of thrombus and the dry and wet weight of thrombus,as well as amount of Fibrinogen (Fg) were observed. Results Compared with model group,the shortening of PT and TT,and the decrease of Fg were obviously suppressed in high dosage SSB group (P