Preparation and dissolution of Wurenchun Dispersible Tablet / 中成药
Chinese Traditional Patent Medicine
; (12)1992.
Article
in Zh
| WPRIM
| ID: wpr-579751
Responsible library:
WPRO
ABSTRACT
AIM:
To prepare Wurenchun Dispersible Tablet(Fructus schisandrae Chinensis)and investigate the dissolution of it.METHODS:
The optimal formulation of Wurenchun Dispersible Tablets was established by the single factor experiments.The dissolution of deoxyschisandrin from Wurenchun Dispersible Tablets was determined by HPLC.RESULTS:
Wurenchun Dispersible Tablets prepared by the mixture of 50 g extraction and 125 g CaHPO_4 plus excipent(MCC∶CMS-Na 3∶1)could disintegrate and disperse well within 3 min in(20?1)℃ water.The dissolution of deoxyschisandrin from Wurenchun Dispersible Tablets was higher than 80% in 15 min.CONCLUSION:
Wurenchun Dispersible Tablets were stable,dissolved fast and completely.The preparation could promote the dissolution of total lignans.
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Traditional Patent Medicine
Year:
1992
Type:
Article