Lipid oxidation and endothelial function in coronary atherosclerosis / 医学研究生学报

ABSTRACT

Objective:To explore the relationship between the coronary atherosclerosis and endothelium function or lipidoxidative function. Methods:All subjects underwent selective coronary angiography.Their age,sex,body mass index,smoking status,blood pressure,plasma and serum of levels of glucose,total cholesterol,triglycerides,high density lipoproteins,non-hingh density lipoproteins,oxidized LDL,endothelin(ET)and nitric oxide(NO)were measured. Results: Subjects were divided into two groups,according to coronary lesion(50 cases),and non-coronary lesion(25 cases).The plasma levels of OxLDL〔(65.31?9.87)mmol vs(46.95?7.74)mmol/L〕and ET 〔(91.92?8.50)ng/L) vs (82.81?7.37)ng/L〕 were higher in group with coronary lesion than those of group with non-coronary lesion (P