Synergism in the cytotoxic effects of nedaplatin combined with adriamycin or mitomycin or Fluorouracil on human liver cancer cell line SMMC7721 in vitro / 医学研究生学报
Journal of Medical Postgraduates
; (12)2003.
Article
in Zh
| WPRIM
| ID: wpr-584011
Responsible library:
WPRO
ABSTRACT
Objective:
To investigate the suppressive effects of nedaplatin on human liver cancer cell line SMMC7721 and the interactions between nedaplatin and adriamycin or mitomycin or fluorouracil.Methods:
The cytotoxic index of nedaplatin alone or combined with other chemotherapy agents on SMMC cells were detected by MTT method.Results:
SMMC was sensitive to nedaplatin with a positive correlation between cytotoxic index and nedaplatin concentration. There were significant synergism in the cytotoxic effects of nedaplatin combined with adriamycin or Mitomycin or Fluorouracil on SMMC cells.Conclusion:
Nedapltin is a promising agent in the treatment of human liver cancer.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Journal of Medical Postgraduates
Year:
2003
Type:
Article