Polyphenolic component of fruit skin of Garcinia mangostana L. and inhibitory effect on acid production by Streptococcus mutans GS-5

ABSTRACT

Which component of polyphenol of Garcinia mangostana L effecting on S. mutans GS-5 causing tooth decay was studied. The materials the microorganism strain Streptococus mutans GS-5 of America. The method: compounds of polyphenol were isolated by thin layer chromatography method. To measure the pH reduction in glycolysis. The result: Using thin layer chromatography on silicagen was isolated 15 bands of flavonoid from the extract of mangostana. The flavonoid component corresponding with Rf 0,80; Rf 0,86 and Rf 0,91 can strongly inhibit the acid production of S.mutans GS-5