Granulocyte colony-stimulating factor and hematonosis / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
; (53)2007.
Article
in Zh
| WPRIM
| ID: wpr-594317
Responsible library:
WPRO
ABSTRACT
Granulocyte colony-stimulating factor is a glycosylated polypeptide chain cell growth factor that can promote proliferation and differentiation of myeloid progenitors and induce maturation of these cells toward terminally differentiated neutrophils.Granulocyte colony-stimulating factor which functions and effects depend on the combination with specific receptor on the surface of effector cells.With the development of gene cloning technology,ganulocyte colony-stimulating factor recombinant products have been widely used in clinic to provide effective means for the treatment of leucopenia,In recent years,we find the therapy of chemotherapeutics combining with granulocyte colony-stimulating factor is effective in refractory/relapsed/elderly cases of acute leukaemia.Currently,granulocyte colony-stimulating factor is one of important and successful hematopoietic cytokines in clinic.
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WPRIM
Language:
Zh
Journal:
Chinese Journal of Tissue Engineering Research
Year:
2007
Type:
Article