Reticulocyte parameters of normal human and its relationship with mature erythrocyte parameters / 国际检验医学杂志

ABSTRACT

Objective To investigate the relationship between the parameters of the red blood cells and the corresponding param‐eters of mature red blood cells .Methods Blood samples of 112 healthy males and 110 healthy females were tested for these reticu‐locyte parameters by using Siemens Advia2120 hematology analyzer .Reference intervals were established .Comparisons between these reticulocyte parameters and the corresponding parameters of mature erythrocytes were drawn .Results Reference intervals for the healthy group recruited in this study were determined as follows .Females ,percentage of reticulocyte (Retic% )0 .45% ~1 .76% ,absolute reticulocyte number(Retic#)(22~86)× 109/L ,mean corpuscular hemoglobin content of reticulocyte(CHr)30 . 1~36 .4 pg ,mean corpuscular volume of reticulocyte(MCVr)99 .5~113 .7 fL .Male ,Retic%0 .54% ~1 .93% ,Retic#(29~104)× 109/L ,CHr32 .6~36 .6 pg ,MCVr97 .6~112 .7 fL .The absolute reticulocyte of male is significantly higher than that of female;MCVr was significantly larger than mean corpuscular volume of mature erythrocytes ,which was also slightly larger in male than that in female;CHr was significantly higher than mean corpuscular hemoglobin of mature erythrocytes while mean corpuscular hemoglobin concentration of large reticulocytes was lower than that of mature erythrocytes;red blood cell volume distribution width of reticulocytes was lower than that of mature erythrocytes;the hemoglobin content distribution width of mature erythrocytes has a higher uniformity compared with reticulocytes .Conclusion The reference ranges of not commonly used parameters of reticulocytes were established ,and were compared with the corresponding parameters of red blood cells .