Analysis of Risk Factors in Adverse Reaction of Cefazolin Drugs by Logistics Model / 中国药房
China Pharmacy
;
(12): 4513-4514,4515, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-605235
ABSTRACT
OBJECTIVE:
To explore the risk factors of adverse reaction of cefazolin drugs by Logistic model.METHODS:
Re-lated information was collected from the information system of our hospital,and SPSS 19.0 software was conducted for statistical analysis.RESULTS:
Totally 855 patients were enrolled,30 of which had adverse reactions(3.51%). According to the results of Logistic analysis,intravenous administration with the concentration of ≥20 mg/ml (OR=7.857,95% CI1.566-39.431,P=0.003) was the risk factor of adverse reaction of cefazolin drugs when single dose was above 2 g (OR=13.75,95% CI2.423-78.028,P1.75 g with ad-ministration time of 000-905 and concentration of above 7 mg/ml. According to the predictive thresholds,the risk of patients with adverse reaction can be predicted to promote safe and effective use of cefazolin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
China Pharmacy
Year:
2015
Type:
Article
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