Optimization of Methanol Extraction Technology for Tripterine in the Fruit of Celastrus monospermus by Orthogonal Design / 中国药房
China Pharmacy
;
(12): 2677-2679, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-620729
ABSTRACT
OBJECTIVE:
To optimize the methanol extraction technology of tripterine in the fruit of Celastrus monospermus.METHODS:
HPLC was adopted to determine the content of tripterine. Using extraction time,extraction times,solid-liquid ratio as investigation factors,extraction rate of tripterine as investigation index,orthogonal test was designed,and verification test was con-ducted.RESULTS:
The optimal methanol extraction technology was as follow as 45% methanol extracting 2 h each time with sol-id-liquid ratio of 18 for 3 times. In the verification test,the average extraction rate of tripterine was 0.917 mg/g(RSD=2.85%, n=3).CONCLUSIONS:
The optimized methanol extraction technology is stable and feasible with high extraction rate,and is suit-able for the extraction of tripterine in the fruit of C. monospermus.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2017
Type:
Article
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