Clinical Analysis of Virus-Associated Hemophagocytic Syndrome in Children / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)1986.
Article
in Zh
| WPRIM
| ID: wpr-638381
Responsible library:
WPRO
ABSTRACT
Objective To increase the awareness of virus-associated hemophagocytic syndrome.Methods Sixteen cases of virus-associated hemophagocytic syndrome were retrospectively analyzed.Results All presented with persistent high fever,cytopenia,hepato-splenomegaly,hepatic dysfunction,hypertriglyceridemia,hyperferritinemia,coagulopathy,hypofibrinogenemia,cytokine storm and a low natural killer cell activity.All patients had lymphohistiocytic accumulation in bone marrow.Treatment with high-dose gamma-globulin and high-dose methylprednisolone.Clinical symptoms and laboratory improved,and five patients died.Conclusion Aggressive early diagnosis and treatment are critical to improve survival.
Full text:
1
Index:
WPRIM
Type of study:
Screening_studies
Language:
Zh
Journal:
Journal of Applied Clinical Pediatrics
Year:
1986
Type:
Article