The Effects of Gonadectomy and Prenatal Testosterone Injection on Galanin Immunoreactive Cells in the Medial Preoptic Area of Rats / 대한해부학회지
Korean Journal of Anatomy
;
: 259-268, 1997.
Article
in Korean
| WPRIM
| ID: wpr-652126
ABSTRACT
Within the medial preoptic area[MPOA], several cytoarchitectonically defined cell groups are sexually dimorphic in their morphology. Specially, the sexual dimorphic nucleus of the preoptic area[SDN-POA] is reported an example of a morphological sex difference in the rat hypothalamus which is influenced by gonadal steroid hormones. Thus, we detemined the distribution of Galanin-immunoreactive[Gal-I] cells and fibers within MPOA and their morphological response to gonadal steroids which is influenced by gonadectomy or prenatal restosterone treatments were observed. The Gal-I cells were appeared within the medial preoptic area. In the males, the volume and number of Gal-I nerve cell bodies were greater than that of females. But the female which treated prenatal testosterone injection had many Gal-I neurons than infact female. And the males that decreased the volume of gonadal hormone by gonadectomy were decreased the volume and number of Gal-I neurons than that of normal males. These results suggest that galaninergic cells within the medial preoptic area are influenced by gonadal steroid hormone[testosterone] in the regulation of sexually dimorphic function.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Preoptic Area
/
Gonadal Steroid Hormones
/
Steroids
/
Testosterone
/
Immunohistochemistry
/
Sex Characteristics
/
Galanin
/
Gonads
/
Hypothalamus
/
Neurons
Limits:
Animals
/
Female
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Anatomy
Year:
1997
Type:
Article
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