A Case of MALT Lymphoma Showing Mikulicz Syndrome / 대한이비인후과학회지

ABSTRACT

Since Mikulicz's description of symptomless hypertrophy of the salivary gland and lacrimal gland, the term, Mikulicz syndrome, has been used to describe enlargement of the salivary gland with or without lacrimal gland involvement occurring in leukemia, lymphosarcoma, sarcoidosis, tuberculosis syphilis, etc. However, there are still a tremendous amount of confusion in the application of the term, Mikulicz syndrome. In Korea, there has been no reported case of Mikulicz syndrome to date. Internationally, it is also extremely rare to spot a reported case of the disease originating primarily from submandibular glands. We would like to report a case in which a 56 year old female patient was reported to have the disease ; she was diagnosed initially as benign lymphoepithelial lesion (BLL) by submandibular biopsy, but later confirmed by lacrimal gland biopsy to have mucosa associated lymphoid tissue (MALT).