Research advances in the effects of thrombospondin-1 on the progress of diabetic retinopathy / 眼科新进展
Recent Advances in Ophthalmology
; (6): 984-987, 2017.
Article
in Zh
| WPRIM
| ID: wpr-657797
Responsible library:
WPRO
ABSTRACT
Thrombospondin-1,an important extracellular matrix glycoprotein,is recognized as an effective endogenous angiogenesis inhibitor and can affect and regulate the adhesion,motility and proliferation of endothelial cells,as well as closely correlated with the development and progress of tumor and neovascular diseases.In recent years,it has been found that Tsp-1 is associated with many pathologic changes in diabetic retinopathy and is critical for the maintenance of retinal vascular balance.And the mechanism of action of TSP-1 and its role in the development of DR will be reviewed in this paper.
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WPRIM
Language:
Zh
Journal:
Recent Advances in Ophthalmology
Year:
2017
Type:
Article