Anterior and posterior cruciate ligament reconstruction under arthroscopy:tendon autografts versus allografts / 中国组织工程研究

ABSTRACT

BACKGROUND: Most domestic studies have shown that there are similar curative effects of allogeneic and autogenous tendons in anterior or posterior cruciate ligament reconstruction. Both of them are good grafts that can achieve satisfactory outcomes. OBJECTIVE: To compare the clinical efficacies of allogeneic and autogenous tendons in anterior and posterior cruciate ligaments reconstruction under arthroscopy. METHODS: A total of 100 patients with knee cruciate ligament rupture undergoing anterior and posterior cruciate ligament reconstruction under arthroscopy were enrolled in this study, and randomly divided into two groups (n=50 per group) autogenous tendon group and allogeneic tendon group. The joint stability and mobility of the two groups were compared before operation and at discharge. The muscle strength recovery, Werner patellofemoral pain score and the Lysholm score of the two groups were evaluated and compared at 1, 3, 6, 9 months after discharge. RESULTS AND CONCLUSION: (1) Joint stability The Lachman test positive rates and axial shift test positive rates in the two groups after operation were significantly better than the baseline (P < 0.05). At discharge, there were no significant differences in Lachman test positive rates and axial shift test positive rates between the two groups. (2) Joint range of motion There were no significant differences in the joint ranges of extension and flexion between the two groups after operation. (3) Follow-up visit Muscle strength, the Werner patellar pain scores and the Lysholm scores in the two groups were significantly improved at discharge (P < 0.05), but there were no significant difference between the two groups at 1, 3, 6, 9 months after discharge. In summary, autologous hamstring tendon and allogeneic tendon have the same clinical therapeutic effects in anterior and posterior cruciate ligament reconstruction under arthroscopy, both of which can achieve good short-term outcomes.