Diagnostic limitation and usefulness of (99m)Tc-DISIDA hepatobiliary scanning on neonatal cholestasis / 소아과
Korean Journal of Pediatrics
; : 737-744, 2006.
Article
in Ko
| WPRIM
| ID: wpr-66796
Responsible library:
WPRO
ABSTRACT
PURPOSE: To assess the usefulness of (99m)Tc-DISIDA scanning in the early evaluation of neonatal cholestasis and to verify the diagnostic value of this test in the differential diagnosis of biliary atresia. METHODS: DISIDA scannings were performed and analyzed in 87 children(58 males and 29 females; age, 18-139 days, mean, 59.1 days) with neonatal cholestasis. Five groups according to the final diagnosis and the results of DISIDA scanning were analyzed by scatter plots using the parameters of age and the level of liver function tests(direct bilirubin, AST, ALT, ALP, GGT). The diagnostic sensitivity, specificity and accuracy of DISIDA scanning in the diagnosis of biliary atresia were compared between a higher bilirubin group and a lower bilirubin group(direct bilirubin level >5 mg/dL vs. 5 mg/dL vs. 9.7 percent for 5 mg/dL), especially if it delays early diagnosis and surgical intervention.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Bilirubin
/
Biliary Atresia
/
Cholestasis
/
Sensitivity and Specificity
/
Early Diagnosis
/
Diagnosis
/
Diagnosis, Differential
/
Hepatitis
/
Liver
Type of study:
Diagnostic_studies
/
Screening_studies
Limits:
Female
/
Humans
/
Male
/
Newborn
Language:
Ko
Journal:
Korean Journal of Pediatrics
Year:
2006
Type:
Article