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Preparation and Characterization of Resveratrol Microemulsions / 中国药师
China Pharmacist ; (12): 414-419, 2015.
Article in Zh | WPRIM | ID: wpr-669683
Responsible library: WPRO
ABSTRACT

Objective:

To prepare resveratrol microemulsions by high pressure homogenization method and characterize the microe-mulsions.

Methods:

Using the particle size, polydispersion index and encapsulation efficiency as the indicators, the independent varia-bles of the preparation were inspected, and the microemulsions were characterized. The stability of resveratrol microemulsions was stud-ied by long term stability test preliminarily.

Results:

The mean particle size, polydispersion index and zeta potential of resveratrol mi-croemulsions was (231 ± 37. 8) nm, 0. 228 ± 0. 047 and ( -42. 5 ± 4. 3) mV, respectively. The microemulsions were found to be small and spherical with smooth surface under a transmission electron microscope. Long term stability studies showed that the microe-mulsions were stable in 3 months after stored at 25℃.

Conclusion:

The preparation process of high pressure homogenization method for resveratrol microemulsions is simple and feasible.
Key words
Full text: 1 Index: WPRIM Language: Zh Journal: China Pharmacist Year: 2015 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: China Pharmacist Year: 2015 Type: Article