Preparation Technology of Buccal Tablets Containing Old Tea Leaf Extract / 中国药师
China Pharmacist
;
(12): 747-749, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-669780
ABSTRACT
Objective:
To prepare old tea buccal tablets using wet granulation method and optimize the preparation technology.Methods:
The amount of each adjuvant was studied by single factor experiments, and the formula of the buccal tablets was optimized by the orthogonal experiments using taste and disintegration time as indices.Results:
The optimal formula was composed of old tea ex-tract 30 g,mannitol 60g,PEG6000 20 g,aspartame 10 g,citric acid 10 g and menthol crystal 1 g. All the tested indices including ap-pearance, hardness and disintegration time met the requirements described in Chinese pharmacopeia.Conclusion:
The preparation technology is reasonable and feasible for the industrial production.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2015
Type:
Article
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