Specific Chromatogram of Fufang Shexiang Injection and Simultaneous Determination of Five Components by GC / 中国药师
China Pharmacist
; (12): 2036-2038, 2015.
Article
in Zh
| WPRIM
| ID: wpr-670162
Responsible library:
WPRO
ABSTRACT
Objective:
To establish the specific chromatogram of Fufang Shexiang injection and simultaneously determine five com-ponents( menthol,borneol,patchouli alcohol,muscone,α-asarone) in the injection by GC.Methods:
The sample solution was extracted by a solid-phase extraction method. The separation was performed on a DB-WAX GC capillary column with an FID detection.Results:
The specific chromatogram had six common peaks, and the similarity was above 0. 91. The five chemical components(menthol,borne-ol,patchouli alcohol,muscone,α-asarone) were well separated and with good linear relationship, the recoveries were between 95. 1 and 102. 6%, and RSD was less than 3. 0%.Conclusion:
The method is simple, accurate and reproducible. The specific chromatogram combined with multi-component determination can reflect the overall quality of Fufang Shexiang injection, which can be used for the quality control of the preparation.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
China Pharmacist
Year:
2015
Type:
Article