Circulating Specific IgG Immune Complexes Activating Complement in Pregnancy Induced Hypertension / 中华围产医学杂志

ABSTRACT

Objective To determine circulating specific IgG immune complexes activating complement(IgG/C3-CIC)concentrations in maternal serum of normal term pregnant women and women with pregnancy induced hypertension(PIH).Methods We detect the serum level of IgG/ C3-CIC and IgG in 115 subjects,including 34 cases of normal pregnant women and 81 cases of PIH women.Results The serums concentrations of IgG/C3-CIC in normal term pregnant women, women with mild PHI,moderate PIH and serve PIH were 0.284?0.18,0.303?0.16,0.483?0.286 and 0.462?0.206,respectively.The serum concentration of IgG in the women were 191.07?112. 92g/L,147.56?47.91 g/L,140.18?32.89 g/L and 125.40?53.24 g/L,respectively.The serum concentration of IgG/C3-CIC in patients with moderate PIH and severe PIH was higher than that in patients with mild PIH and normal term pregnant women(P