X-chromosome Inactivation Patterns in Korean Women with Idiopathic Recurrent Spontaneous Abortion
Journal of Korean Medical Science
; : 258-262, 2004.
Article
in En
| WPRIM
| ID: wpr-67696
Responsible library:
WPRO
ABSTRACT
Recurrent spontaneous abortion (RSA) defines as two or more consecutive losses at or =90%) and 4 (8.9%) had mild skewed inactivation (> or =85%). In 54 heterozygous control subjects, 5 (9.3%) women showed extreme skewed X inactivation and 7 (13.0%) had mild one. The frequency of skewed X inactivation between RSA patients and control group was not significantly different (p>0.05). This finding suggests that skewed x romosome be not associated with unexplained RSA patients.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Lymphocytes
/
Abortion, Spontaneous
/
Dosage Compensation, Genetic
/
Abortion, Habitual
/
DNA Methylation
/
Heterozygote
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Korea
/
Genetic Linkage
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Country/Region as subject:
Asia
Language:
En
Journal:
Journal of Korean Medical Science
Year:
2004
Type:
Article