Hyperinsulinemic Hypoglycemia Caused by Acute Reduction of Renal Function on an Eldery Patient Without Diabetes
Journal of the Korean Geriatrics Society
; : 34-39, 2015.
Article
in Ko
| WPRIM
| ID: wpr-67732
Responsible library:
WPRO
ABSTRACT
In patient with renal failure, hypoglycemia may develop because of decreased caloric intake, diminished renal insulin degradation and clearance, reduced renal gluconeogenesis and hepatic glucose production, impaired release of counter-regulatory hormone such as glucagon and epinephrine. We report here on a 80-year-old female patient with hypoglycemia due to endogenous hyperinsulinemia with acute kidney injury. She had chronic kidney disease and had no history of diabetes mellitus or insulin use. She had experienced recurrent hypoglycemia despite of intravenous dextrose injection and eventually generalized tonic clonic seizure occurred as a result of hypoglycemia. As serum creatinine level decreases, serum insulin and C-peptide level decreased and hypoglycemia was not occurred. We present this case along with a review of the literature.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Seizures
/
C-Peptide
/
Energy Intake
/
Glucagon
/
Epinephrine
/
Creatinine
/
Diabetes Mellitus
/
Renal Insufficiency
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Renal Insufficiency, Chronic
/
Acute Kidney Injury
Limits:
Aged
/
Aged80
/
Female
/
Humans
Language:
Ko
Journal:
Journal of the Korean Geriatrics Society
Year:
2015
Type:
Article