Value of neutrophil lymphocyte ratio and coagulation parameters for diagnosing hypercoagulable state in patients with malignant tumor / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 661-663,667, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-692725
ABSTRACT
Objective To investigate the clinical value of neutrophil lymphocyte ratio(NLR)and coagula-tion parameters for diagnosing hypercoagulable state in the patients with malignant tumor.Methods A total of 683 cases of malignant tumor and 200 cases of benign tumor in this hospital from December 2014 to Decem-ber 2016 were selected as the malignant tumor group and benign tumor group respectively.The malignant tumor group was further divided into the hypercoagulability group and non hypercoagulable group according to the combination of hypercoagulability.Meanwhile 143 individuals undergoing healthy physical examination were selected as the control group.The changes of neutrophil count(NC),lymphocyte count(LC),NLR,D-dinner,fibrinogen(Fib),platelet count(PLT)and platelet distribution width(PDW)were observed.The sen-sitivity and specificity of NLR and coagulation parameters for diagnosing hypercoagulable state were analyzed. Results The NC level and NLR in the malignant tumor group were higher than those in the benign tumor group and control group,while the LC level was lower than that in the benign tumor group and control group, the difference was statistically significant(P< 0.05).The D-D,Fib and PDW levels in the malignant tumor group were higher than those in the benign tumor group and control group,while the PLT level was lower than that in the benign tumor group and control group,the difference was statistically significant(P<0.05).
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
International Journal of Laboratory Medicine
Year:
2018
Type:
Article
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