Vascular endothelial growth factor: a potential therapeutic target for ischemic stroke / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
; (12): 47-50, 2018.
Article
in Zh
| WPRIM
| ID: wpr-692948
Responsible library:
WPRO
ABSTRACT
Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis and vascular regeneration after cerebral ischemia.On one hand,VEGF plays a neuroprotective effect by promoting angiogenesis and neurogenesis;on the other hand,VEGF induced endothelial permeability can cause blood-brain barrier (BBB) dysfunction.Exercise preconditioning can up-regulate the expression of VEGF and reduce the ischemic brain damage by enhancing the cerebral microvascular integrity.VEGF can be used as a therapeutic target for ischemic stroke.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
International Journal of Cerebrovascular Diseases
Year:
2018
Type:
Article