Gastric Mucosal Damage Induced by Dual Anti-platelet Therapy and its Prevention in Elderly / 胃肠病学

ABSTRACT

With the increase of elderly patients with cardiovascular and cerebrovascular diseases,dual anti-platelet therapy (DAPT) is becoming more and more commonly used in the elderly,and at the same time gastric mucosal damage induced by DAPT has become a common issue in clinical practice.Therefore,prevention of gastric mucosal injury induced by DAPT in elderly has turned to be a research hot-spot.Because of the degeneration of gastric mucosal barrier,the injury and invasive factors endured by the elderly were more severe and prominent,and gastric mucosal damage induced by DAPT will be more frequent and severe.Therefore,the gastric mucosal protective strategies for elderly with DAPT should be different from that of young and middle-aged patients.In this article,the gastric mucosal damage induced by DAPT and its protective strategies in elderly were briefly reviewed.