ECG characteristics ,preventive and therapeutic strategy of ventricular arrhythmias induced by second-ary hypokalemia / 心血管康复医学杂志

ABSTRACT

Objective:To explore related clinical manifestations ,ECG characteristics and therapeutic strategy of ven-tricular arrhythmias induced by secondary hypokalemia .Methods:Clinical data of 184 patients ,who were diagnosed as ventricular arrhythmias induced by secondary hypokalemia in our hospital from Jan 2013 to Nov 2015 ,were retro-spectively analyzed .ECG characteristics and clinical manifestations were analyzed ,blood potassium concentration and incidence of ventricular arrhythmia were compared between before and after treatment .According to blood po-tassium concentration ,patients were divided into mild hypokalemia group (n＝91 ,3.01～3.5mmol/L ,mild group) , medium hypokalemia group (n＝78 ,2.51～3.00mmol/L ,medium group) and severe hypokalemia group (n＝15 ,＜2.5mmol/L ,severe group).ECG condition was compared among these groups .Results: Main clinical manifesta-tions included palpitations ,chest tightness ,fatigue ,hypotension and short of breath etc .,and severe patients can present as coma ,intestinal paralysis and syncope etc .Among ECG manifestations ,premature ventricular systole was the most frequent [75 (40.8%)] ,and the second was frequent premature atrial systole [69 (37.5%)].Compared with mild group ,there were significant rise in percentage of positive ECG changes (50.5% vs.79.5%,100%) in medium group and severe group (P＝0.001 both) ,but there was no significant difference between medium and se-vere group , P＝0.120. Compared with before treatment ,after treatment ,there was significant rise in blood potas-sium concentration [ (2.5 ± 1.1) mmol/L vs.(4.4 ± 1.7) mmol/L] ,and significant reductions in percentages of ventricular premature contraction (86.96% vs .25.00%) and persistent ventricular tachycardia (8.70% vs.0) in these patients ,P＝0.001 all .Conclusion:Along with blood potassium level reduces ,percentage of patients with ven-tricular arrhythmias induced by secondary hypokalemia and abnormal ECG rises .Timely ECG and blood potassium examinations should be performed in these patients for timely treatment .