Agreement between corneal-compensated intraocular pressure (IOPcc) and five corrected intraocular pressures and the correlation of ocular biometries with IOPcc and Goldmann correlated intraocular pressure / 眼科新进展

ABSTRACT

Objective To compare the agreement between corneal-compensated intraocular pressure (IOPcc) measured by ocular response analyzer (ORA) and 5 corrected intraocular pressures from Sirius anterior system,and analyze the correlation of ocular biometries with IOPcc and Goldmann-correlated IOP (IOPg).Methods Together 90 eyes of 90 patients,aged 18-37 (24.47 ± 5.57) years,without refractive surgery contraindications undergoing myopic laser treatment were enrolled in this study.Each eye was measured 3 times by Sirius anterior system,with the best results of IOPcc and IOPg was selected.And patients' corneal biomechanical parameters were measured using an ORA (Reichert,Inc.,USA).The IOPg from ORA were entered into the 5 IOP formulas embedded in Sirius anterior system to generate the corrected IOPs,which were recorded as the Dresdner corrected IOP,Ehlers corrected IOP,Kohlhaas corrected IOP,Orssengo/Pye corrected IOP and Shah corrected IOP,accordingly.Meanwhile the agreement of the 5 corrected IOPs and the IOP measured non-contact tonometer with IOPcc was analyzed,respectively.Corneal biomechanics,including corneal hysteresis and corneal resistance factor,and ocular biometries were also recorded,and the correlation of these parameters with IOPcc and IOPg was assessed with correlation coefficient.Resuits The pair comparison of IOPcc and Kohlhaas corrected IOP was statistically significant (P ＜ 0.05).Dresdner corrected IOP and Orssengo/Pye corrected IOP showed a good agreement with IOPcc,and the 95％ limits of agreements (LoA) were (-2.09 ～2.55)mmHg (1 kPa=7.5 mmHg) and (-2.38～2.37) mmHg,respectively.The 95％LoA of Dresdner's corrected IOP and IOPcc was the narrowest.No statistical significance was found between IOPcc and corneal hysteresis,corneal resistance factor,ocular biometries,but there was a positive correlation between IOPg and corneal resistance factor,central corneal thickness,and corneal volume (all P ＜ 0.05).Conclusion Dresdner and Orssengo/Pye corrected IOP had a good agreement with IOPcc,and most ocular biometries have a little effect on IOPcc.