Efficacy evaluation of compound polyethylene glycol electrolyte solution dosage and administration method on bowel preparation before colonoscopy / 中国内镜杂志
China Journal of Endoscopy
; (12): 23-27, 2018.
Article
in Zh
| WPRIM
| ID: wpr-702921
Responsible library:
WPRO
ABSTRACT
Objective To assess the efficacy of bowel preparation and tolerability, adverse reactions, re-examination willingness in different dose and taking method of compound polyethylene glycol electrolyte solution (PEG) before colonoscopy. Method This was a prospective, randomized, single-blind trial. From March 2017 to April 2017, 200 patients underwent colonoscopy were randomized to 3 group as 2L group (n = 60), (2+1)L group (n = 75) or 3L group (n = 65). The primary outcome was preparation quality from procedure photos using the Boston Bowel Preparation Scale. Additional aims of this study were to compare patient's tolerability, side reaction, and the re-examination willingness. Results Over the course of the study we identified 184 eligible outpatients to participate in the study, including 2L group (n = 58), (2+1)L group (n = 70) and 3L group (n = 56). The average of BBPS scores for (2+1)L group and 3L group were higher than 2L group's score (P < 0.05). The scores according to BBPS of the (2+1)L group and 3L group were similar (P > 0.05) but the score of right colon of 3L group was higher than (2+1)L group (P < 0.05). The tolerability, adverse reactions and re-examination willingness of 2L group and (2+1)L group were better than 3L group (P < 0.05). Conclusions The (2+1)L PEG preparation for colonoscopy had higher efficacy than 2L PEG, reduced the adverse reaction of patients and improved the tolerance and the re-examination willingness.
Full text:
1
Index:
WPRIM
Type of study:
Clinical_trials
/
Prognostic_studies
Language:
Zh
Journal:
China Journal of Endoscopy
Year:
2018
Type:
Article