The application of Doppler ultrasonography in children′s transplant renal artery stenosis / 中华超声影像学杂志

ABSTRACT

Objective To explore the value of color Doppler ultrasonography in diagnosis of transplant renal artery stenosis( TRAS) of children . Methods The results of ultrasound examination and clinical data of 82 kidney transplant children with suspected TRAS were retrospectively analyzed . According to the results of the CTA ,the enrolled children were divided into a stenosis group with 21 cases and a non-stenosis group with 61 cases . The differences of ultrasound hemodynamic parameters between the two groups were compared . The hemodynamic parameters and cutoff values of prediction of TRAS were determined according to the ROC curve ,and the corresponding sensitivity and specificity were calculated . Logistic regression was used to screen TRAS independent predictors . Results Compared with the non-stenosis group ,the peak systolic velocity ( PSV ) of the renal aorta ,the renal aorta PSV/interlobular artery PSV ( post PSV ratio ) and acceleration time ( AT ) of interlobular artery in the stenosis group were significantly higher ,but the PSV of the interlobular artery was lower ( all P ＜ 0 .05 ) . Differences of indicators between the two groups can be used to predict TRAS . Through the ROC curve the peak systolic velocity of the renal aorta and the interlobular artery were 218 .5 cm/s and 25 .5 cm/s ,respectively ,the post PSV ratio was 7 .2 ,and the AT of intervein arterial was 67 .5 ms ,the sensitivity and specificity were the highest ,which could be used as the ultrasound screening threshold . The PSV of the interlobular artery can be used as an independent predictor of TRAS . Conclusions Analysis of hemodyamic parameters of transplanted kidney arteries by Doppler ultrasonography might be useful in predicting TRAS in children .