Prevalence and risk factors for chronic kidney disease among patients with type 2 diabetes mellitus managed in community health centers in Shanghai / 中华内分泌代谢杂志

ABSTRACT

Objective To estimate the prevalence of chronic kidney disease and to identify influencing factors among patients enrolled in diabetes management by the community health centers in Shanghai. Methods A questionnaire survey and physical examination were conducted in patients with type 2 diabetes through a random sampling method. Eligible date of 1 618 subjects were enrolled in the study. Estimated glomerular filtration rate was calculated according to equation of the Modification of Diet in Renal Disease Study for serum creatinine. Logistic regression was performed to examine the association between risk factors and chronic kidney disease. Results The prevalence of chronic kidney disease was 43.4%, of which 16.1%were in Stage 1, 14.8%in Stage 2, 11.6%in Stage 3, and 1.0%in Stage 4/5 in the total of 1 618 patients, but only 3.6% of the patients as defined in this study were aware of their condition. A higher prevalence of chronic kidney disease in females than that in males ( 47. 3% vs 37.8%). The prevalence of chronic kidney disease increased with age (χ2tend＝38.663,P<0.01). Female gender, older age, lower education, lower monthly income per capital, long duration of diabetes, uncontrolled glycosylated hemoglobin, uncontrolled systolic blood pressure, and uncontrolled triglycerides, were influencing factors of chronic kidney disease. Conclusion The patients under diabetes management in community health centers had higher prevalence of chronic kidney disease with lower awareness. Patients with type 2 diabetes should be encouraged to control blood glucose, blood pressure and blood lipids, to reduce the risk for chronic kidney disease. 而下降,2、3期均随年龄增大而升高(2 期 χ2趋势＝34.626,3 期,均 P<0.01) .城乡患病率总体上无差别,仅见3期患病率市区高于郊区(14.4%对9.2%, χ2＝10.465,P<0.01).按糖尿病病程长短进行分层发现,总的患病率随病程延长而升高 ,2、3期也呈现同样趋势( 2 期,3 期,均 P<0.05,图1) .