Extent of central lymph node dissection for papillary thyroid carcinoma in the isthmus
Annals of Surgical Treatment and Research
;
: 229-234, 2018.
Article
in English
| WPRIM
| ID: wpr-714539
ABSTRACT
PURPOSE:
The incidence of papillary thyroid carcinoma (PTC) arising from the isthmus is low; however, these tumors have aggressive clinical and pathological features. Moreover, the existing guidelines regarding the extent of surgery for this type of tumor are unclear.METHODS:
This study enrolled 282 patients who underwent total thyroidectomy with bilateral central lymph node dissection. The patients were divided into 2 groups based on the location of the median line of the PTC. Group I included patients in whom the median line was located between the lateral margins of the trachea; group II included all others. We compared the 2 groups and conducted a multivariate analysis to assess risk factors for contralateral node metastasis from a PTC arising from the isthmus.RESULTS:
Patients in group I had significantly higher frequencies of extrathyroidal extension and central lymph node metastasis. Group I also had a higher frequency of contralateral node metastasis, and a tumor size >1.0 cm was identified as an independent risk factor for contralateral node metastasis among patients in this group.CONCLUSION:
Bilateral central lymph node dissection could be considered for patients with isthmic PTCs >1.0 cm in size who have clinically suspicious node metastasis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thyroid Gland
/
Thyroidectomy
/
Trachea
/
Thyroid Neoplasms
/
Incidence
/
Multivariate Analysis
/
Risk Factors
/
Lymph Node Excision
/
Lymph Nodes
/
Neoplasm Metastasis
Type of study:
Etiology study
/
Practice guideline
/
Incidence study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Annals of Surgical Treatment and Research
Year:
2018
Type:
Article
Similar
MEDLINE
...
LILACS
LIS