Comparison of Sporadic Sclerotic Fibroma and Solitary Fibrous Tumor in the Oral Cavity
Yonsei Medical Journal
; : 535-539, 2007.
Article
in En
| WPRIM
| ID: wpr-71483
Responsible library:
WPRO
ABSTRACT
Sporadic sclerotic fibroma (SF) and solitary fibrous tumor (SFT) arising in the oral cavity are very rare. In this report, we describe two cases of oral pathology, one involving SF and the other involving SFT. Both cases presented with well- circumscribed, firm nodules with similar gross findings. However, the histologic findings of the SF and SFT showed rather distinct features. The SF was composed of hyalinized sclerotic collagen bundles arranged in a whorled pattern, whereas the SFT was formed by spindles cells arranged in hypo- and hypercellular areas. The immunohistochemical findings were similar in both cases; there was positivity for vimentin, CD34, and CD99, but bcl-2 positivity was only seen in the SFT. Although their histopathologies are similar, SF and SFT should be considered in the differential diagnosis of soft tissue tumors in the oral cavity.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Vimentin
/
Mouth Neoplasms
/
Immunohistochemistry
/
Antigens, CD
/
Cell Adhesion Molecules
/
Neoplasms, Fibrous Tissue
/
Antigens, CD34
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Proto-Oncogene Proteins c-bcl-2
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Diagnosis, Differential
/
Fibroma
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
Yonsei Medical Journal
Year:
2007
Type:
Article