Pineal and Suprasellar Germinoma Cooccurence with Vertebra Plana: A Case Report
Brain Tumor Research and Treatment
;
: 73-77, 2018.
Article
in English
| WPRIM
| ID: wpr-717502
ABSTRACT
Germinoma is the most common type of intracranial germ cell tumors (GCTs). Pineal gland and suprasellar region are the most frequent sites of central nervous system (CNS) involvement. Intracranial masses caused by Langerhans cell histiocytosis (LCH) mimics features of CNS GCTs. LCH frequently involve spine and is the most common cause of vertebra plana in children. A 15-year-old boy presented with progressing symptoms of polydipsia, polyuria, general headache, nausea and severe back pain. Brain MRI showed brain tumor with simultaneous involvement of suprasellar region and pineal gland. An excisional biopsy of suprasellar mass was done. The pathologic assessment confirmed the diagnosis of germinoma. Patient's treatment continued accordingly. A spine MRI, done due to persistent backache, showed a vertebra plana. We reevaluated the primary diagnosis suspecting LCH. Germinoma of CNS was confirmed and a biopsy of vertebral lesion resulted in hemangioma. Thus we report a case of CNS germinoma with co-occurrence of vertebra plana. We emphasized the importance of histopathologic diagnosis of pineal/suprasellar masses and primary investigation of other CNS regions including spine for possible metastasis or comorbidities.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pineal Gland
/
Polyuria
/
Spine
/
Biopsy
/
Brain
/
Brain Neoplasms
/
Magnetic Resonance Imaging
/
Comorbidity
/
Central Nervous System
/
Histiocytosis, Langerhans-Cell
Type of study:
Diagnostic study
Limits:
Adolescent
/
Child
/
Humans
/
Male
Language:
English
Journal:
Brain Tumor Research and Treatment
Year:
2018
Type:
Article
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