Two Cases of Cytomegalovirus Pneumonia after CD34 Selected Autologous Stem Cell Transplantation
Korean Journal of Hematology
; : 134-137, 2006.
Article
in Ko
| WPRIM
| ID: wpr-720229
Responsible library:
WPRO
ABSTRACT
Cytomegalovirus (CMV) pneumonia is an important cause of treatment related mortality after allogeneic stem cell transplantation (SCT) and autologous SCT, particularly in a CD34 selected setting. There is little known about the immune reconstitution pertaining to the CMV after CD34 selected SCT. However, several studies have suggested there is more profound immunodeficiency early in the CD34 selected population compared with the unselected population. We encountered two fatal cases of CMV pneumonia at the CD34 selected SCT for T-cell lymphoblastic lymphoma and high-risk breast cancer that was confirmed through a lung biopsy and bronchoalveolar lavage. In conclusion, autologous CD34 selected CMV seropositive recipients need to be monitored in a similar manner to allogeneic recipients.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Pneumonia
/
Stem Cells
/
Biopsy
/
Breast Neoplasms
/
T-Lymphocytes
/
Mortality
/
Bronchoalveolar Lavage
/
Cytomegalovirus
/
Stem Cell Transplantation
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Type of study:
Prognostic_studies
Language:
Ko
Journal:
Korean Journal of Hematology
Year:
2006
Type:
Article