Malignant-looking thyroid nodules with size reduction: core needle biopsy results
Ultrasonography
;
: 327-334, 2016.
Article
in English
| WPRIM
| ID: wpr-731058
ABSTRACT
PURPOSE:
The aim of this study was to evaluate whether malignant-looking thyroid nodules with size reduction were malignant or not.METHODS:
From November 2010 to July 2011, we retrospectively enrolled 16 patients with 16 nodules (11 females and five males; mean age, 55 years) who underwent core needle biopsy (CNB), and whose thyroid nodules had malignant ultrasonographic (US) features, although they showed size reduction (>20% decrease in maximum diameter) during the follow-up period (mean, 37±27 months). The histologic findings of the CNB specimen were reviewed and correlated with the US findings. US studies were analyzed for their internal content, shape, margin, echogenicity, the presence of microcalcification and macrocalcification, inner isoechoic rim, and low-echoic halo.RESULTS:
All nodules were confirmed as benign by CNB. Pathologic analysis was available for 12 CNB specimens. US imaging showed central hypoechogenicity or marked hypoechogenicity in all cases and a peripheral isoechoic rim in 15 nodules. US-pathologic correlation showed that the central hypoechoic area was primarily composed of fibrosis (12/12) and hemorrhage (8/12) and that the isoechoic rim was composed of follicular cells.CONCLUSION:
In our study, the CNB results of all of the malignant-looking thyroid nodules with size reduction were benign and were primarily composed of internal fibrosis and hemorrhage. Understanding these US and pathologic features could prevent repeated fine-needle aspiration or unnecessary diagnostic surgery.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thyroid Gland
/
Fibrosis
/
Retrospective Studies
/
Follow-Up Studies
/
Ultrasonography
/
Thyroid Nodule
/
Biopsy, Fine-Needle
/
Biopsy, Large-Core Needle
/
Hemorrhage
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Ultrasonography
Year:
2016
Type:
Article
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