Use of Spectral-Domain Optical Coherence Tomography to Analyze Macular Thickness According to Refractive Error
Journal of the Korean Ophthalmological Society
; : 1286-1295, 2011.
Article
in Ko
| WPRIM
| ID: wpr-73147
Responsible library:
WPRO
ABSTRACT
PURPOSE: To investigate the correlation of macular retinal thickness and refractive error using spectral-domain optical coherence tomography (SD-OCT). METHODS: A total of 120 eyes with no posterior abnormalities were enrolled in the present study. Subjects were divided into 3 groups based on their spherical equivalent. Visual acuity, refraction, slit lamp examination, tonometry and fundus examination were performed. Retinal thickness between the RPE and IS/OS junction was measured at the fovea, 1 mm (inner ring) and 2 mm (outer ring) superiorly, inferiorly, nasally and temporally using SD-OCT. Overall average thickness, average foveal thickness, and the inner and outer ring macular thickness were measured. RESULTS: The average foveal thickness was significantly greater in the high myopic eyes than in the low to moderate myopic and emmetropic eyes (p = 0.001). However, the RPE-IS/OS junction thickness of the foveola and the outer macular thickness were significantly lower (p = 0.001, p = 0.002) in the high myopic eyes. There was a weak, but significant negative correlation between refractive error and average foveal thickness (r = -0.38, p = 0.001). A positive correlation was found between refractive error and the RPE-IS/OS junction thickness (r = 0.40, p = 0.001). CONCLUSIONS: Macular retinal thickness is related to refractive error in normal subjects. Effects of eyeball elongation are more apparent in high myopic eyes than in low to moderate myopic eyes. A significant decline in the RPE-IS/OS junction thickness suggests the photoreceptor outer segments in the foveola are damaged in high myopic eyes.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Refractive Errors
/
Retinaldehyde
/
Visual Acuity
/
Tomography, Optical Coherence
/
Eye
/
Manometry
/
Myopia
Language:
Ko
Journal:
Journal of the Korean Ophthalmological Society
Year:
2011
Type:
Article