Clinical study of Xiere-Zhuyu-Paishi decoction and auxiliary lithotripsy for the patients withupper ureteral calculi on the effect of stone removal and renal colic relief / 国际中医中药杂志

ABSTRACT

Objective To observe the effect of stone removal and relieving renal colic with Xiere-Zhuyu-Paishi decoction and auxiliary lithotripsy in patients with upper ureteral calculi. Methods A total of 80 patients with upper ureteral calculi were divided into the observation group and the control group according to the random number table method, with 40 in each group. Both groups were treated with extracorporeal shock wave lithotripsy (ESWL) as the basic treatment. Besides, the control group added the western medicine, such as pain relieving, spasmodic and anti-infection while, the observation group with Xiere-Zhuyu-Paishi decoction. Both groups were treated for 4 weeks. After 1 courses of treatment, the curative effect was evaluated. The effect of lithotripsy (lithotripsy success rate, stone clearance rate, stone expulsion time), renal colic improvement (renal colic rate, analgesic drug usage rate, pain visual analogue VAS score) and WHOQOL-BREF scores were compared. Results After treatment, the total efficiency of observation group was 92.5％ (37/40), while the control group was 75％ (25/40), and the difference was statistically significant (Z=-3.082, P=0.004). After treatment, the observation group stone clearance rate was 92％ (36/40), while the control group was 72.5％ (29/40), and the difference was statistically significant (χ2=3.986, P=0.031). After treatment, the incidence of renal colic of the observation group was 12.5％ (5/40), while the control group was 32.5％ (13/40), and the difference was statistically significant (χ2=3.146, P=0.037). The analgesic drug usage rate in the observation group was 5％ (2/40), while the the control group was 25％ (10/40), and the difference was statistically significant (χ2=4.021, P=0.019). After treatment, the observation group lithecbole time, pain VAS score levels in the observation group was significantly lower than those in the control group (t=6.261,5.743, all Ps<0.01). After treatment, the WHOQL-BREF score, the physiological domain score, psychological field score, social relationship domain score, environment the field score in the observation group were significantly higher than those of control group (t values were 6.731, 4.342, 5.064, 4.521, 5.128, all Ps<0.01).Conclusions The application of Xiere-Zhuyu-Paishi decoction and auxiliary lithotripsy in patients with upper ureteral calculi can promote stone removal in upper ureteral stones, alleviate renal colic and improve the quality of life of the patients.