Usefulness of Total IgE in Predicting Positive Allergen Specific IgE Tests in Korean Subjects / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 660-667, 2010.
Article
in Korean
| WPRIM
| ID: wpr-73302
ABSTRACT
BACKGROUND:
Total IgE levels in allergic patients tend to be higher than those in healthy individuals. We evaluated the usefulness of total IgE levels in predicting positive results of allergen specific IgEs in multiple allergen simultaneous tests.METHODS:
A total of 133 patients with allergic symptoms were evaluated. Allergen specific IgEs were detected using 3 different kits Allergy screen (R-biopharm, Germany), AdvanSure Allergy Screen (LG Life Science, Korea) and Polycheck allergy (Biocheck Co., Germany). Total IgE was measured by turbidoimmunometric assay (LX-2200, Eiken Chemical Co., Japan). The patients were divided into high (> or =170 IU/mL) and low ( or =50%. Allergen specific IgEs to these two allergens showed good correlation with total IgE (correlation coefficients >0.5).CONCLUSIONS:
Total IgE appears to be useful in predicting positive results in allergen specific IgE tests to common allergens. The specific IgEs to D. farinae and D. pteronyssinus showed good correlation with total IgE. However, for other allergens, significant differences were observed among different test kits, and the standardization of allergens in multiple allergen simultaneous tests is needed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reagent Kits, Diagnostic
/
Immunoglobulin E
/
Allergens
/
Predictive Value of Tests
/
Dermatophagoides farinae
/
Dermatophagoides pteronyssinus
/
Republic of Korea
/
Hypersensitivity, Immediate
Type of study:
Prognostic study
Limits:
Aged80
/
Animals
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Korean
Journal:
The Korean Journal of Laboratory Medicine
Year:
2010
Type:
Article
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