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Exposure-preceding-outcome regarding time sequence among cohort studies in real world / 中华流行病学杂志
Chinese Journal of Epidemiology ; (12): 858-861, 2018.
Article in Zh | WPRIM | ID: wpr-738060
Responsible library: WPRO
ABSTRACT
One of the commonly accepted merits of cohort studies (CSs) refers to the exposure precedes outcome superior to other observational designs. We use Directed Acyclic Graphs to construct a causal graph among research populations under CSs. We notice that the substitution of research population in place of a susceptible one can be used for effect estimation. Its correctness depends on the outcome-free status of the substituted population and the performance of both screening and diagnosis regarding the outcomes under study at baseline. The temporal precedence of exposure over outcome occurs theoretically, despite the opposite happens in realities. Correct effect estimate is affected by both the suitability of population substitution and the validities of outcome identification and exclusion.
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Full text: 1 Index: WPRIM Main subject: Research Design / Mass Screening / Epidemiologic Methods / Causality / Confounding Factors, Epidemiologic / Cohort Studies Type of study: Etiology_studies / Observational_studies Language: Zh Journal: Chinese Journal of Epidemiology Year: 2018 Type: Article
Full text: 1 Index: WPRIM Main subject: Research Design / Mass Screening / Epidemiologic Methods / Causality / Confounding Factors, Epidemiologic / Cohort Studies Type of study: Etiology_studies / Observational_studies Language: Zh Journal: Chinese Journal of Epidemiology Year: 2018 Type: Article