Durable Response of Androgen Receptor-Positive Male Breast Cancer to Goserelin / 한국유방암학회지
Journal of Breast Cancer
; : 141-148, 2019.
Article
in En
| WPRIM
| ID: wpr-738408
Responsible library:
WPRO
ABSTRACT
The luteinizing hormone-releasing hormone/androgen receptor (LHRH/AR) pathway is a promising treatment target in a subgroup of female patients with triple-negative breast cancer (TNBC). However, very little is known about the efficacy of this strategy in male patients with TNBC. In this report, we describe a male patient with AR-positive TNBC who was successfully treated using an LHRH agonist after pretreatment with several lines of chemotherapy and achieved a durable response. We also review the existing evidence supporting LHRH- and AR-targeted therapy for this rare disease.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Lutein
/
Receptors, Androgen
/
Gonadotropin-Releasing Hormone
/
Goserelin
/
Breast Neoplasms, Male
/
Rare Diseases
/
Drug Therapy
/
Triple Negative Breast Neoplasms
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Journal of Breast Cancer
Year:
2019
Type:
Article