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Durable Response of Androgen Receptor-Positive Male Breast Cancer to Goserelin / 한국유방암학회지
Journal of Breast Cancer ; : 141-148, 2019.
Article in En | WPRIM | ID: wpr-738408
Responsible library: WPRO
ABSTRACT
The luteinizing hormone-releasing hormone/androgen receptor (LHRH/AR) pathway is a promising treatment target in a subgroup of female patients with triple-negative breast cancer (TNBC). However, very little is known about the efficacy of this strategy in male patients with TNBC. In this report, we describe a male patient with AR-positive TNBC who was successfully treated using an LHRH agonist after pretreatment with several lines of chemotherapy and achieved a durable response. We also review the existing evidence supporting LHRH- and AR-targeted therapy for this rare disease.
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Full text: 1 Index: WPRIM Main subject: Lutein / Receptors, Androgen / Gonadotropin-Releasing Hormone / Goserelin / Breast Neoplasms, Male / Rare Diseases / Drug Therapy / Triple Negative Breast Neoplasms Limits: Female / Humans / Male Language: En Journal: Journal of Breast Cancer Year: 2019 Type: Article
Full text: 1 Index: WPRIM Main subject: Lutein / Receptors, Androgen / Gonadotropin-Releasing Hormone / Goserelin / Breast Neoplasms, Male / Rare Diseases / Drug Therapy / Triple Negative Breast Neoplasms Limits: Female / Humans / Male Language: En Journal: Journal of Breast Cancer Year: 2019 Type: Article